News

Cannabis withdrawal trial

Researchers from the University of Sydney are looking for participants in a trial program to evaluate the safety and efficacy of lithium in the management of cannabis withdrawal.

Behaviour interventions have been shown to assist in managing problematic cannabis use, withdrawal symptoms such as sleep difficulties, increased anger and aggression, irritability, nervousness and anxiety may be a barrier to achieving and maintaining abstinence.

Trial coordinator Dr Jennifer Johnston said there are currently no evidence-based pharmacotherapies (the treatment of a disease through the use of drugs) for the management of cannabis withdrawal.

“The availability of a safe and effective medication would be valuable both in supporting the attainment of abstinence and as a means of attracting cannabis users into treatment,” she said.

Lithium is a mood-stabilising medication commonly used for the management of bipolar affective disorder. The findings of a recent human trial by the current investigators provided preliminary evidence of the potential use of lithium in the management of cannabis withdrawal.

In what is thought to be a world first study, they are now seeking a further 30-40 participants to do a “double-blind, randomised, placebo controlled trial”. Participants must be over 18 years of age and will be screened by medical officers. They will be admitted to the inpatient detoxification unit at Riverlands Drug and Alcohol Centre in Lismore for seven days and administered lithium (500mg b.d.) or placebo. Participants will be monitored daily for self-reported cannabis withdrawal symptoms and lithium adverse effects and toxicity, with follow-up interviews conducted 14- 30- and 90- days post discharge. Blood, urine and saliva samples will be taken throughout the course of the trial to monitor lithium, oxytocin and THC levels.

If you are interested in finding out more about the trial, please contact Dr Jennifer Johnston on 1800 757 110 or email jennifer.johnston@sydney.edu.au.


Join the Community.

Get your local news, your way.

Stay Connected

Update your news preferences and get the latest news delivered to your inbox.

A bishop of balance built his flock

SADDENED: Service for Bishop Satterthwaite at Lismore Cathedral

Bishop Satterthwaite was given a warm farewell this week.

South Lismore Primary’s Miss World hopeful says ‘she can’

SHE CAN: Miss World finalist Janaya Everingham outside her old primary school.

Lismore's Miss World Finalist makes it happen for Variety charity

BUDGET 2016: Tax cuts for firms pulling in up to $10m

Australian Federal Treasurer Scott Morrison speaks at the despatch box during the delivery of the 2016-17 Federal Budget in the House of Representatives at Parliament House in Canberra,

It will cost the federal government $5.3 billion in lost revenue

Latest deals and offers

Lismore Eisteddfod is in need of funds to secure its future

Supporters of Lismore's Esiteddfod need to find funds to keep show running at City Hall.

A bishop of balance built his flock

SADDENED: Service for Bishop Satterthwaite at Lismore Cathedral

Bishop Satterthwaite was given a warm farewell this week.

South Lismore Primary’s Miss World hopeful says ‘she can’

SHE CAN: Miss World finalist Janaya Everingham outside her old primary school.

Lismore's Miss World Finalist makes it happen for Variety charity

BUDGET 2016: Tax cuts for firms pulling in up to $10m

Australian Federal Treasurer Scott Morrison speaks at the despatch box during the delivery of the 2016-17 Federal Budget in the House of Representatives at Parliament House in Canberra,

It will cost the federal government $5.3 billion in lost revenue

Lismore has diversity Byron had

(From left) Christopher Woodward, Shanon Robb, Lora-Jean Damen and Sabrina Major model the clothes for the new fashion event Threads which will take place at the Back Alley Gallery. Photo Marc Stapelberg / The Northern Star

Lismore has what Byron had - vibrancy and diversity.

Maudeville is back, brighter and shinier than ever

DIVA: Maude Boat as MC of the Cabaret Show at a previous Tropical Fruit’s New Year Eve Party in Lismore.

IN A city full of divas, only one reigns supreme: Maude Boate.

Enjoy a barefoot belly-dance as well as a sketch

Stacey Walker and Sasha Fox from the Barefoot Gypsies look forward to Gypsy Nights to be held at their studio in Carrington Street on Saturday night. Photo Cathy Adams / The Northern Star

Let The Barefoot Gypsies entertain you

Spectacular Crash as Corvette Flips at Drag Races

Corvette flips at 350kmh.

Driver walks away from 350kmh crash in Texas.

Star Wars: Force Awakens told in Emojis

Disney has released an emoji version of The Force Awakens.

To commemorate Star Wars Day, Disney releases emoji version of film on a smart...

NYPD join dance challenge

New York Police respond to NZ dance challenge.

New York's finest accept Kiwi dance challenge.

How a sacked real estate agent made $725k in four months

Agent is now under investigation by the industry watchdog

VIDEO: Art Deco fan pays $835,000 for Imperial Hotel

No Caption

Iconic "Impy" sold at a bargan price to bidder who loves Art Deco.

RBA warns of future apartment oversupply

Toowoomba: Crest Apartments and Burke & Wills, Ruthven Street ( view from Neil Street) Photo Bev Lacey / The Chronicle

RBA says oversupply of apartments poses risk to household finances